Single-cell
Proteomics

Overview

CyTOF® XT System allows researchers to dive deep into single-cell proteomics by detecting over 50 markers

Overview

CyTOF® XT System allows researchers to dive deep into single-cell proteomics by detecting over 50 markers

Overview

CyTOF® XT System allows researchers to dive deep into single-cell proteomics by detecting over 50 markers

Our Work

Unraveling the Complexity of the Immune System

Understanding the intricate behavior of individual cells is critical in today’s biomedical research, especially for immune system analysis, disease progression, and therapeutic response.

CyTOF™ XT Systems

Overview

Our CyTOF® XT Systems allows researchers to dive deep into single-cell proteomics by capturing highly multiplexed surface and functional markers simultaneously, uncovering unique biomarkers with precision. This unparalleled insight empowers researchers to fully explore the heterogeneity of cell populations.

Maxpar® Direct Immune Profiling Assay™

Overview

The Maxpar® Direct Immune Profiling Assay™, coupled with the CyTOF XT platform, offers a standardized, high-parameter analysis of immune cell populations, making it easier to obtain accurate and actionable data faster. Whether you are studying immune response in cancer, autoimmunity, or infectious diseases, Single Cell Proteomics solutions provide the critical insights necessary for advancing translational research and therapeutic development.
Unraveling the Complexity of the Immune System

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Our Work

Unraveling the Complexity of the Immune System

Flow is a disadvantaged biomarker screening tool where CyTOF is the widest screening tool capturing the most relevant immune metrics.

Traditional flow cytometry is constrained

Expansive cell types identified

additional immune functional layer

CyTOF XT automates much of the workflow, significantly reducing the hands-on time required by researchers and enabling the processing of large numbers of samples efficiently, without sacrificing data quality.

CyTOF is Unconstrained

Our Work

Unparalleled Multiplexing Capability

CyTOF XT detects over 50 markers at once, far exceeding the limits of traditional flow cytometry. This enables a comprehensive analysis of immune populations and functional responses in a single experiment.

Using metal isotopes rather than fluorescent dyes, CyTOF eliminates the common issue of spectral overlap found in traditional flow cytometry, providing cleaner and more precise data without the need for compensation.

No Spectral Overlap

Our Work

Using metal isotopes rather than fluorescent dyes, CyTOF eliminates the common issue of spectral overlap found in traditional flow cytometry, providing cleaner and more precise data without the need for compensation.

High-Throughput Automation

CyTOF XT automates much of the workflow, significantly reducing the hands-on time required by researchers and enabling the processing of large numbers of samples efficiently, without sacrificing data quality.

Our Work

Comprehensive Immune Profiling

Our Work

With the Maxpar® Direct Immune Profiling Assay™, researchers can measure 37 immune cell populations using a simple single-tube workflow, providing detailed insights into immune function and facilitating faster, more informed decision-making in both preclinical and clinical settings.

A must-see session highlighting what could be missing in spectral flow cytometry results. Learn more about a head-to-head comparison of intracellular staining panels using a spectral flow cytometer and the CyTOF XT mass cytometer.​

Jennifer Snyder-Cappione, PhD​
Assistant Professor of Virology, ​
Immunology & Microbiology​
Boston University School of Medicine

1.
Status Quo
2.
Standard Bio Tools
Unraveling the Complexity of the Immune System

Traditional flow cytometry faces limitations such as spectral overlap, limited multiplexing (typically fewer than 20 markers), and the need for multiple rounds of staining. This results in a higher chance of experimental error, longer processing times, and incomplete data.

Status Quo

(Fluorescence-Based Flow Cytometry)

Traditional flow cytometry faces limitations such as spectral overlap, limited multiplexing (typically fewer than 20 markers), and the need for multiple rounds of staining. This results in a higher chance of experimental error, longer processing times, and incomplete data.

Limitations

Spectral Overlap

< 20 Markers

Staining Redundancy

Status Quo

(Fluorescence-Based Flow Cytometry)

Limitations

Spectral Overlap

< 20 Markers

Staining Redundancy

Traditional flow cytometry faces limitations such as spectral overlap, limited multiplexing (typically fewer than 20 markers), and the need for multiple rounds of staining. This results in a higher chance of experimental error, longer processing times, and incomplete data.

Our Solution

Remove the limitations.

Unique scale and high signal resolution

Simultaneously detect over 50 markers without spectral overlap

Higher-content, more reliable dataset in a single analysis

Faster, more accurate insights into complex cellular behaviors.

Limitations

Spectral Overlap

< 20 Markers

Staining Redundancy

Our Solutions

Our Work

Case Studies

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Remove the limitations.

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Improved Accuracy. over 50 markers. FASTER INSIGHTS. More Reliable.
Improved Accuracy. over 50 markers. FASTER INSIGHTS. More Reliable.

CyTOF XT Instrument

CyTOF XT removes these limitations with its unique scale and high signal resolution, allowing researchers to simultaneously detect over 50 markers without spectral overlap. This provides a higher-content, more reliable dataset in a single analysis, leading to faster, more accurate insights into complex cellular behaviors.

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Our Work

Case Studies

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Overview

High-Throughput Automation

CyTOF XT automates much of the workflow, significantly reducing the hands-on time required by researchers and enabling the processing of large numbers of samples efficiently, without sacrificing data quality.

Overview

No Spectral Overlap:

Using metal isotopes rather than fluorescent dyes, CyTOF eliminates the common issue of spectral overlap found in traditional flow cytometry, providing cleaner and more precise data.

Overview

Comprehensive Immune Profiling

With the Maxpar® Direct Immune Profiling Assay™, researchers can measure 37 immune cell populations from a single tube of blood, providing detailed insights into immune function and facilitating faster, more informed decision-making in both preclinical and clinical settings.

Unraveling the complexity of the immune system

Our Work

Understanding the intricate behavior of individual cells is critical in today’s biomedical research, especially for immune system analysis, disease progression, and therapeutic response.

Our Work

CyTOF™ XT Systems

Our CyTOF® XT Systems allows researchers to dive deep into single-cell proteomics by capturing highly multiplexed surface and functional markers simultaneously, uncovering unique biomarkers with precision. This unparalleled insight empowers researchers to fully explore the heterogeneity of cell populations.

Maxpar® Direct Immune Profiling Assay™

The Maxpar® Direct Immune Profiling Assay™, coupled with the CyTOF XT platform, offers a standardized, high-parameter analysis of immune cell populations, making it easier to obtain accurate and actionable data faster. Whether you are studying immune response in cancer, autoimmunity, or infectious diseases, Single Cell Proteomics solutions provide the critical insights necessary for advancing translational research and therapeutic development.

Lorem ipsum dolor sit amet consec tetur adipisicing elit sed consec tetur adipisicing. Lorem ipsum dolor sit amet consec tetur adipisicing elit sed consec tetur adipisicing.

Jennifer Snyder-Cappione, PhD​
Assistant Professor of Virology, ​
Immunology & Microbiology​
Boston University School of Medicine

Our Work

Comprehensive Immune Profiling

Using metal isotopes rather than fluorescent dyes, CyTOF eliminates the common issue of spectral overlap found in traditional flow cytometry, providing cleaner and more precise data without the need for compensation.

Jennifer Snyder-Cappione, PhD​
Assistant Professor of Virology, ​
Immunology & Microbiology​
Boston University School of Medicine

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