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Single-cell
Proteomics
Overview
CyTOF® XT System allows researchers to dive deep into single-cell proteomics by detecting over 50 markers
Overview
CyTOF® XT System allows researchers to dive deep into single-cell proteomics by detecting over 50 markers
Overview
CyTOF® XT System allows researchers to dive deep into single-cell proteomics by detecting over 50 markers
Our Work
Unraveling the Complexity of the Immune System
Understanding the intricate behavior of individual cells is critical in today’s biomedical research, especially for immune system analysis, disease progression, and therapeutic response.
CyTOF™ XT Systems
Overview
Our CyTOF® XT Systems allows researchers to dive deep into single-cell proteomics by capturing highly multiplexed surface and functional markers simultaneously, uncovering unique biomarkers with precision. This unparalleled insight empowers researchers to fully explore the heterogeneity of cell populations.
Maxpar® Direct Immune Profiling Assay™
Overview
The Maxpar® Direct Immune Profiling Assay™, coupled with the CyTOF XT platform, offers a standardized, high-parameter analysis of immune cell populations, making it easier to obtain accurate and actionable data faster. Whether you are studying immune response in cancer, autoimmunity, or infectious diseases, Single Cell Proteomics solutions provide the critical insights necessary for advancing translational research and therapeutic development.
Unraveling the Complexity of the Immune System
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Our Work
Unraveling the Complexity of the Immune System
Flow is a disadvantaged biomarker screening tool where CyTOF is the widest screening tool capturing the most relevant immune metrics.
Traditional flow cytometry is constrained
Expansive cell types identified
additional immune functional layer
CyTOF XT automates much of the workflow, significantly reducing the hands-on time required by researchers and enabling the processing of large numbers of samples efficiently, without sacrificing data quality.
CyTOF is Unconstrained
Our Work
Unparalleled Multiplexing Capability
CyTOF XT detects over 50 markers at once, far exceeding the limits of traditional flow cytometry. This enables a comprehensive analysis of immune populations and functional responses in a single experiment.
Using metal isotopes rather than fluorescent dyes, CyTOF eliminates the common issue of spectral overlap found in traditional flow cytometry, providing cleaner and more precise data without the need for compensation.
No Spectral Overlap
Our Work
Using metal isotopes rather than fluorescent dyes, CyTOF eliminates the common issue of spectral overlap found in traditional flow cytometry, providing cleaner and more precise data without the need for compensation.
High-Throughput Automation
CyTOF XT automates much of the workflow, significantly reducing the hands-on time required by researchers and enabling the processing of large numbers of samples efficiently, without sacrificing data quality.
Our Work
Comprehensive Immune Profiling
Our Work
With the Maxpar® Direct Immune Profiling Assay™, researchers can measure 37 immune cell populations using a simple single-tube workflow, providing detailed insights into immune function and facilitating faster, more informed decision-making in both preclinical and clinical settings.
A must-see session highlighting what could be missing in spectral flow cytometry results. Learn more about a head-to-head comparison of intracellular staining panels using a spectral flow cytometer and the CyTOF XT mass cytometer.
Jennifer Snyder-Cappione, PhD
Assistant Professor of Virology,
Immunology & Microbiology
Boston University School of Medicine
Status Quo
Standard Bio Tools
Unraveling the Complexity of the Immune System
Traditional flow cytometry faces limitations such as spectral overlap, limited multiplexing (typically fewer than 20 markers), and the need for multiple rounds of staining. This results in a higher chance of experimental error, longer processing times, and incomplete data.
Status Quo
(Fluorescence-Based Flow Cytometry)
Traditional flow cytometry faces limitations such as spectral overlap, limited multiplexing (typically fewer than 20 markers), and the need for multiple rounds of staining. This results in a higher chance of experimental error, longer processing times, and incomplete data.
Limitations
Spectral Overlap
< 20 Markers
Staining Redundancy
Status Quo
(Fluorescence-Based Flow Cytometry)
Limitations
Spectral Overlap
< 20 Markers
Staining Redundancy
Traditional flow cytometry faces limitations such as spectral overlap, limited multiplexing (typically fewer than 20 markers), and the need for multiple rounds of staining. This results in a higher chance of experimental error, longer processing times, and incomplete data.
Our Solution
Remove the limitations.
Unique scale and high signal resolution
Simultaneously detect over 50 markers without spectral overlap
Higher-content, more reliable dataset in a single analysis
Faster, more accurate insights into complex cellular behaviors.
Limitations
Spectral Overlap
< 20 Markers
Staining Redundancy
Our Solutions
Our Work
Case Studies
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Remove the limitations.
CyTOF XT removes these limitations with its unique scale and high signal resolution, allowing researchers to simultaneously detect over 50 markers without spectral overlap. This provides a higher-content, more reliable dataset in a single analysis, leading to faster, more accurate insights into complex cellular behaviors.
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Improved Accuracy.
over 50 markers.
FASTER INSIGHTS.
More Reliable.
Improved Accuracy.
over 50 markers.
FASTER INSIGHTS.
More Reliable.
CyTOF XT Instrument
CyTOF XT removes these limitations with its unique scale and high signal resolution, allowing researchers to simultaneously detect over 50 markers without spectral overlap. This provides a higher-content, more reliable dataset in a single analysis, leading to faster, more accurate insights into complex cellular behaviors.
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Our Work
Case Studies
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Overview
High-Throughput Automation
CyTOF XT automates much of the workflow, significantly reducing the hands-on time required by researchers and enabling the processing of large numbers of samples efficiently, without sacrificing data quality.
Overview
No Spectral Overlap:
Using metal isotopes rather than fluorescent dyes, CyTOF eliminates the common issue of spectral overlap found in traditional flow cytometry, providing cleaner and more precise data.
Overview
Comprehensive Immune Profiling
With the Maxpar® Direct Immune Profiling Assay™, researchers can measure 37 immune cell populations from a single tube of blood, providing detailed insights into immune function and facilitating faster, more informed decision-making in both preclinical and clinical settings.
Understanding Single-Cells
Our Work
Understanding the intricate behavior of individual cells is critical in today’s biomedical research, especially for immune system analysis, disease progression, and therapeutic response.
CyTOF™ XT Systems
Overview
Our CyTOF® XT Systems allows researchers to dive deep into single-cell proteomics by capturing highly multiplexed surface and functional markers simultaneously, uncovering unique biomarkers with precision. This unparalleled insight empowers researchers to fully explore the heterogeneity of cell populations.
Maxpar® Direct Immune Profiling Assay™
Overview
The Maxpar® Direct Immune Profiling Assay™, coupled with the CyTOF XT platform, offers a standardized, high-parameter analysis of immune cell populations, making it easier to obtain accurate and actionable data faster. Whether you are studying immune response in cancer, autoimmunity, or infectious diseases, Single Cell Proteomics solutions provide the critical insights necessary for advancing translational research and therapeutic development.
CyTOF Reagents
Overview
A collection of metal-conjugated antibodies used for labeling specific cell markers in CyTOF XT, enabling in-depth analysis across various applications.
Lorem ipsum dolor sit amet consec tetur adipisicing elit sed consec tetur adipisicing. Lorem ipsum dolor sit amet consec tetur adipisicing elit sed consec tetur adipisicing.
Jennifer Snyder-Cappione, PhD
Assistant Professor of Virology,
Immunology & Microbiology
Boston University School of Medicine
Our Work
Comprehensive Immune Profiling
Using metal isotopes rather than fluorescent dyes, CyTOF eliminates the common issue of spectral overlap found in traditional flow cytometry, providing cleaner and more precise data without the need for compensation.
Jennifer Snyder-Cappione, PhD
Assistant Professor of Virology,
Immunology & Microbiology
Boston University School of Medicine
Unraveling the complexity of the immune system
Our Work
Understanding the intricate behavior of individual cells is critical in today’s biomedical research, especially for immune system analysis, disease progression, and therapeutic response.
Our Work
CyTOF™ XT Systems
Our CyTOF® XT Systems allows researchers to dive deep into single-cell proteomics by capturing highly multiplexed surface and functional markers simultaneously, uncovering unique biomarkers with precision. This unparalleled insight empowers researchers to fully explore the heterogeneity of cell populations.
Maxpar® Direct Immune Profiling Assay™
The Maxpar® Direct Immune Profiling Assay™, coupled with the CyTOF XT platform, offers a standardized, high-parameter analysis of immune cell populations, making it easier to obtain accurate and actionable data faster. Whether you are studying immune response in cancer, autoimmunity, or infectious diseases, Single Cell Proteomics solutions provide the critical insights necessary for advancing translational research and therapeutic development.
Lorem ipsum dolor sit amet consec tetur adipisicing elit sed consec tetur adipisicing. Lorem ipsum dolor sit amet consec tetur adipisicing elit sed consec tetur adipisicing.
Jennifer Snyder-Cappione, PhD
Assistant Professor of Virology,
Immunology & Microbiology
Boston University School of Medicine
Our Work
Comprehensive Immune Profiling
Using metal isotopes rather than fluorescent dyes, CyTOF eliminates the common issue of spectral overlap found in traditional flow cytometry, providing cleaner and more precise data without the need for compensation.
Jennifer Snyder-Cappione, PhD
Assistant Professor of Virology,
Immunology & Microbiology
Boston University School of Medicine